The sermon emphasizes the importance of lifting God above all problems and challenges in life. It encourages believers to focus on their vertical relationship with God, which is personal and involves faith, worship, prayer, and obedience. The sermon also highlights the significance of horizontal relationships with others, which reflect one's relationship with God. It calls for love, compassion, service, sacrifice, forgiveness, and reconciliation in these relationships. The message is rooted in the teachings of Acts 1:1-8, emphasizing the need for believers to act on their faith and live on mission for Jesus Christ.